The recognition of the approach as the benchmark in cell/particle counting stems from the extraordinary precision and accuracy of its particle sizing and counts, particularly as compared to manual and imaging based technologies (accuracies on the order of 98% for Coulter counters versus 75-80% for manual and vision-based systems). The resulting occlusion of the aperture by the particles yields a measurable change in electric impedance that can be directly and precisely correlated to cell size/volume. The technique involves the application of an electric field across a micron-sized aperture and hydrodynamically focusing single particles through the aperture. A critical breakthrough in cell/particle counting technologies was the development of the Coulter technique by Wallace Coulter over 50 years ago. Particle and cell counting is used for a variety of applications including routine cell culture, hematological analysis, and industrial controls 1-5. Vi-CELL XR INTRODUCTION 1 1.1 MANUAL DESCRIPTION Scope.
Labeling updates, go to and download the most recent manual or system help for your instrument.
This article has been cited by other articles in PMC.Ĭomputer with software authorized by Beckman Coulter.
0 kommentar(er)
